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  • Toward New Clinical Diagnostics and Therapeutics
    Vadim V. Demidov
    978-3-319-42226-8
    2016
    Edition 1
    • Reviews prospective RCA-based therapeutics, including RCA-derived DNA nanoparticles that strongly bind to cancer cells, along with DNA nanoclews and DNA origami nanostructrures as vehicles for intracellular delivery of various drugs
    • Expands readers’ understanding of sensor systems for expediting detection of RCA products by using probe-tagged magnetic nanobeads
    • Maximizes reader insights into novel RCA diagnostics, such as PNA openers-assisted RCA for detection of single target cells, ramified RCA for identifying the disease-related SNPs, RNA-primed RCA for detection of microbial pathogens and in situ RCA diagnosis of cancer cells and malignant tissues
    • Presents innovative methods for quasi-exponential enhancement of RCA-generated signals, such as nicking enzyme-assisted cascade RCA and RCA coupled with loop-mediated amplification
    • Includes supplementary material: sn.pub/extras

    €180

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