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United Nations Sustainable Development Goals (SDGs)
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Toward New Clinical Diagnostics and TherapeuticsVadim V. Demidov978-3-319-42226-82016 Edition 1- Reviews prospective RCA-based therapeutics, including RCA-derived DNA nanoparticles that strongly bind to cancer cells, along with DNA nanoclews and DNA origami nanostructrures as vehicles for intracellular delivery of various drugs
- Expands readers’ understanding of sensor systems for expediting detection of RCA products by using probe-tagged magnetic nanobeads
- Maximizes reader insights into novel RCA diagnostics, such as PNA openers-assisted RCA for detection of single target cells, ramified RCA for identifying the disease-related SNPs, RNA-primed RCA for detection of microbial pathogens and in situ RCA diagnosis of cancer cells and malignant tissues
- Presents innovative methods for quasi-exponential enhancement of RCA-generated signals, such as nicking enzyme-assisted cascade RCA and RCA coupled with loop-mediated amplification
- Includes supplementary material: sn.pub/extras
€180