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  • Arnab De
    978-3-319-14965-3
    2015
    Edition 1
    • Nominated as an outstanding Ph.D. thesis by Columbia University, New York, USA
    • Insightful and in-depth evaluation of the evidence for K63-linked regulatory ubiquitination in regulating cell-signalling in vitro
    • First theses to directly test the role of regulatory ubiquitination in NF-kB signaling in vivo
    • Reports the generation of a knock-in mouse that expresses a mutated form of A20 selectively lacking the deubiquitinase activity
    • Critically determines the role of the deubiquitinase function of A20 in limiting inflammatory responses in vivo

    €180

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