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  • Methods and Protocols
    Tian Jin; Dale Hereld
    978-1-60761-198-1
    2009
    Edition 1
    • Describes a breadth of uniquely suited model systems for analysis of chemotaxis, including bacteria, Dictyostelium, yeast, Drosophila, zebrafish, neurons, and immune and tumor cells
    • Examines phenomena related to chemotaxis, including chemotropism, phototaxis, and electrotaxis
    • Details the application of cutting-edge technologies for stimulating cells with chemoattractants and analyzing their resulting cellular behaviors
    • Covers a variety of state-of-the-art microscopic methods for visualizing the migration of cells in tissues and the spatiotemporal dynamics of chemotaxis signaling molecules
    • Provides step-by-step functional assays for a variety of components involved in chemotaxis, including cell-surface receptors, downstream effectors, and cytoskeletal components
    • Explores the quantitative description of chemoattractant gradients and computational approaches for modeling the signaling networks that underlie gradient sensing
    • Includes supplementary material: sn.pub/extras

    Get access as part of Springer Protocols.

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